scientific studies

Clinical studies on Phosphatidylserine

Studies in the elderly

Double-blind, placebo-controlled clinical studies of Phosphatidylserine show improvements in memory and also in motivation in elderly people with varying degrees of memory and cognitive deficits: 

1. Phosphatidylserine improves memory function in people with age-related memory decline (ARM). 

2. Phosphatidylserine improves behaviour and memory function in elderly people in "moderate to severe cognitive decline". 

3. Phosphatidylserine in the treatment of Alzheimer's disease: results of a multicentre study. 

4. Phosphatidylserine improves mood and social well-being in the elderly: observations from clinical studies. 

5. Phosphatidylserine has an activating effect on brain physiology: E.E.G. tracings, P.E.T. imagery.


Modes of action

Biochemistry of Phosphatidylserine, an essential component of neuronal membranes. Phosphatidylserine supplementation is based on the protection and stabilisation of neuronal membranes. The result is a physiological stimulation of the trans-membrane processes of neurotransmission.


An overview of experimental studies : 

1. Phosphatidylserine acts against the physiological ageing of neuronal membranes. 

2. Phosphatidylserine acts against the weakening of neurotransmissions associated with aging. 

3. Phosphatidylserine prevents age-related loss of dendritic density.


Phosphatidylserine in the French medical press

Medical journals such as Le Quotidien du Médecin, Nutranews, Protéus Network, have discussed the value of Phosphatidylserine supplementation in feature articles, including: 

1. Phyto-nutrients against brain ageing. 

2. A food supplement against age-related memory problems. 

3. GPC, Galantamine, PS, the new anti-ageing brain nutrients. 

4. Phosphatidylserine (PS) and age-related brain damage.

Bibliography and Scientific Dossier

The references of the international scientific publications dealing with Phosphatidylserine are reported according to the following thematic classification: 

1. Clinical definition of "age-related memory decline": work by Dr. Crook. 

2. Clinical studies in "age-related memory decline": Phosphatidylserine studied by Dr Crook. 

3. Open clinical studies in elderly people with memory and cognitive deficits. 

4. Clinical studies in people with Alzheimer's disease. 

5. Double-blind clinical studies in elderly people with memory and cognitive deficits. 

6. Activating effect on brain physiology in humans. 

7. Protection and stabilisation of neuronal membranes (experimental). 

8. Physiological activation of neurotransmissions (experimental). 

9. Animal cognitive models (experimental). 

10. Phosphatidylserine in the French medical press.

Download all the studies carried out on Memory: