effi-science/e-sciences
Vincaria, for joint problems
Vincaria extract (Uncaria tomentosa) is traditionally used in the treatment of joint inflammation. Vincaria is a plant that grows in the Amazon rainforest, as well as in other tropical areas of Mexico and Latin America.
A treatment for joint inflammation
This plant is traditionally used in Peru to alleviate rheumatic inflammatory phenomena, and also to protect the digestive system. Particularly rich in anti-oxidant substances (alkaloids), Vincaria extracts (Uncaria tomentosa) are of great interest to today's leading scientific research.
Recent research activity (clinical, in vitro, and in vivo studies) tends to confirm the beneficial properties of this plant, which has long been used to soothe joints. It is important to provide an adequate titration of active substances for the plant extracts, in order to obtain the expected joint benefits.
We use Vincaria in the composition of our food supplement Cartilamine Phyto.
Bibliographic references
Komal Mehta, Jayesh Gala, Surendra Bhasale, Sattayasheel Naik, Millind Modak, Harshad Thakur, Nivedita Deo and Mark JS Miller
Comparison of glucosamine sulfate and a polyherbal supplement for the relief of osteoarthritis of the knee: a randomized controlled trial [ISRCTN25438351]
BMC Complementary and Alternative Medicine 2007, 7:34 doi:10.1186/1472-6882-7-34
This article is available from: http://www.biomedcentral.com/1472-6882/7/34
Miller MJS, Ahmed S, Bobrowski P, Haqqi TM: Suppression of human cartilage degradation and chondrocyte activation by a unique mineral supplement (sierrasil™) and a cat's claw extract, vincaria®. J Amer Nutr Assoc 2004, 7:32-39.
Sandoval-Chacin J.H. et al, Antiinflammatory actions of cat's claw: the role of NF-kB, Aliment Pharmacol. Ther, 1998, 12:1279-1289.
Aguilar J.L. et al, Anti-inflammatory activity of two different extracts of Uncaria tomentosa, Journal of Ethnopharmacology, 2002, 81:271-276.
Mur E et al, Randomized double blind trial of an extract from the pentacyclic alkaloid-chemotype of Uncaria tomentosa for the treatment of rheumatoid arthritis, J. Rheumatol, 2002 Apr, 29(4):678-681.
Piscoya J. et al, Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanism of action of the species Uncaria guianensis, Inflame Research, 2001, 50(9):442-448
Cisneros F.J. et al, An Uncaria tomentosa extract protects mice against ozone-induced lung inflammation, J. Ethnopharmacol, 2005 Jan 15, 96(3):355-64.
Sandoval M, Charbonnet RM, Okuhama N, Roberts J, Krenova Z, Trentacosti AM, Miller MJS:
Cat's claw inhibits TNF production and scavenges free radicals: role in cytoprotection. Free Radical
Biol Med 2000, 29:71-78.
Sandoval M, Okuhama NN, Zhang X-J, Condezo LA, Lao J, Angeles FM, Bobrowski P, Miller MJS: Anti-inflammatory and antioxidant activities of cat's claw (Uncaria tomentosa and Uncaria guianensis) are independent of their alkaloid content. Phytomedicine 2002, 9:325-337.
Obregan LE: Cat's claw, Uncaria genus. In Botanical, Chemical and Pharmacological Studies of Uncaria tomentosa (Wiild.) D.C. (Rubiaceae) and Uncaria guianensis (Aubl.) Gmel Instituto de Fitotherapia Americano. Lima; 1995.